A&E attendance following infection with COVID-19

Accident and emergency (AE) attendance in England following infection with SARS-CoV-2 Omicron or Delta

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How to cite: Accident and emergency (AE) attendance in England following infection with SARS-CoV-2 Omicron or Delta Daniel J. Grint, Kevin Wing, Hamish P. Gibbs, Stephen JW Evans, Elizabeth Williamson, Krishnan Bhaskaran, Helen I McDonald, Alex J. Walker, David Evans, George Hickman, Rohini Mathur, Anna Schultze, Christopher T Rentsch, John Tazare, Ian J Douglas, Helen J. Curtis, Caroline E Morton, Sebastian Bacon, Simon Davy, Brian MacKenna, Peter Inglesby, Richard Croker, John Parry, Frank Hester, Sam Harper, Nicholas J DeVito, Will Hulme, Chris Bates, Jonathon Cockburn, Amir Mehrkar, Ben Goldacre, Rosalind M. Eggo, Laurie Tomlinson medRxiv 2022.05.03.22274602; doi: https://doi.org/10.1101/2022.05.03.22274602

Abstract

The SARS-CoV-2 Omicron variant is increasing in prevalence around the world. Accurate estimation of disease severity associated with Omicron is critical for pandemic planning. We found lower risk of accident and emergency (AE) attendance following SARS-CoV-2 infection with Omicron compared to Delta (HR: 0.39 (95% CI: 0.30 – 0.51; P<.0001). For AE attendances that lead to hospital admission, Omicron was associated with an 85% lower hazard compared with Delta (HR: 0.14 (95% CI: 0.09 – 0.24; P<.0001)).