Project #200:
Burden of Neurodegenerative Disease 2020-2024

Healthcare planners need information about neurological diseases like dementia, motor neurone disease and Parkinson’s disease. For example, they need to know how often people have diseases of different types (‘incidence’), how many people are living with different diseases (‘prevalence’), survival from diagnosis, and age at diagnosis.

With this application, we will use the data from OpenSafely. This means that we can use consistent methods in each region of the England. It also means we can use data from GPs, hospital admission, and death to find as many people who are affected by neurodegenerative diseases as possible.

We will calculate the incidence, prevalence, age at diagnosis, survival from diagnosis and case fatality for a wide range of neurological diseases, from the very rare to the very common. We will also see whether the estimates for commoner diseases like dementia are different in people of different ethnicities, ages, levels of deprivation and sex in different regions of England., and the effect of the COVID-19 pandemic on these illnesses.